Unique IL-13Rα2/STAT3 mediated IL-13 regulation detected in lung conventional dendritic cells, 24 h post viral vector vaccination

This study demonstrates that 24 h following viral vector-based vaccination IL-13Rα2 functions as a master sensor on conventional dendritic cells (cDCs), abetted by high protein stability coupled with minimal mRNA expression, to rapidly regulate DC mediated IL-13 responses at the lung mucosae, unlike...

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Detalles Bibliográficos
Autores principales: Roy, Sreeja, Liu, Ho-Ying, Jaeson, Muhammad Irwan, Deimel, Lachlan Paul, Ranasinghe, Charani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978450/
https://www.ncbi.nlm.nih.gov/pubmed/31974500
http://dx.doi.org/10.1038/s41598-020-57815-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978450/
https://www.ncbi.nlm.nih.gov/pubmed/31974500
http://dx.doi.org/10.1038/s41598-020-57815-z

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