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Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy: A Translational Study

Disopyramide is effective and safe in patients with obstructive hypertrophic cardiomyopathy. However, its cellular and molecular mechanisms of action are unknown. We tested disopyramide in cardiomyocytes from the septum of surgical myectomy patients: disopyramide inhibits multiple ion channels, lead...

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Detalles Bibliográficos
Autores principales:	Coppini, Raffaele, Ferrantini, Cecilia, Pioner, Josè Manuel, Santini, Lorenzo, Wang, Zhinuo J., Palandri, Chiara, Scardigli, Marina, Vitale, Giulia, Sacconi, Leonardo, Stefàno, Pierluigi, Flink, Laura, Riedy, Katherine, Pavone, Francesco Saverio, Cerbai, Elisabetta, Poggesi, Corrado, Mugelli, Alessandro, Bueno-Orovio, Alfonso, Olivotto, Iacopo, Sherrid, Mark V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	PRECLINICAL RESEARCH
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978554/ https://www.ncbi.nlm.nih.gov/pubmed/31998849 http://dx.doi.org/10.1016/j.jacbts.2019.06.004

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