Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report

Merkel cell carcinoma (MCC) is a rare, rapidly proliferating skin cancer that commonly metastasizes to regional lymph nodes. We present the case of a 73-year-old woman with a history of MCC and non-Hodgkin B-cell lymphoma who presented with second-degree heart block (Mobitz type II) caused by an int...

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Autores principales: Kazemi, Nazanin Yeganeh, Jain, Christopher, Bois, Melanie C., Behfar, Atta, Olivier, Kenneth, Markovic, Svetomir N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978596/
https://www.ncbi.nlm.nih.gov/pubmed/31993571
http://dx.doi.org/10.1016/j.mayocpiqo.2019.09.005
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author Kazemi, Nazanin Yeganeh
Jain, Christopher
Bois, Melanie C.
Behfar, Atta
Olivier, Kenneth
Markovic, Svetomir N.
author_facet Kazemi, Nazanin Yeganeh
Jain, Christopher
Bois, Melanie C.
Behfar, Atta
Olivier, Kenneth
Markovic, Svetomir N.
author_sort Kazemi, Nazanin Yeganeh
collection PubMed
description Merkel cell carcinoma (MCC) is a rare, rapidly proliferating skin cancer that commonly metastasizes to regional lymph nodes. We present the case of a 73-year-old woman with a history of MCC and non-Hodgkin B-cell lymphoma who presented with second-degree heart block (Mobitz type II) caused by an interatrial mass. Temporary pacing was required before biopsy, which revealed metastatic MCC. Treatment included permanent pacing, anti–programmed cell death ligand 1 immunotherapy, and radiation to the heart resulting in notable decrease in tumor size and normalized cardiac rhythm.
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spelling pubmed-69785962020-01-28 Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report Kazemi, Nazanin Yeganeh Jain, Christopher Bois, Melanie C. Behfar, Atta Olivier, Kenneth Markovic, Svetomir N. Mayo Clin Proc Innov Qual Outcomes Case Report Merkel cell carcinoma (MCC) is a rare, rapidly proliferating skin cancer that commonly metastasizes to regional lymph nodes. We present the case of a 73-year-old woman with a history of MCC and non-Hodgkin B-cell lymphoma who presented with second-degree heart block (Mobitz type II) caused by an interatrial mass. Temporary pacing was required before biopsy, which revealed metastatic MCC. Treatment included permanent pacing, anti–programmed cell death ligand 1 immunotherapy, and radiation to the heart resulting in notable decrease in tumor size and normalized cardiac rhythm. Elsevier 2019-11-22 /pmc/articles/PMC6978596/ /pubmed/31993571 http://dx.doi.org/10.1016/j.mayocpiqo.2019.09.005 Text en © 2019 THE AUTHORS https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kazemi, Nazanin Yeganeh
Jain, Christopher
Bois, Melanie C.
Behfar, Atta
Olivier, Kenneth
Markovic, Svetomir N.
Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report
title Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report
title_full Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report
title_fullStr Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report
title_full_unstemmed Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report
title_short Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report
title_sort heart block caused by cardiac metastasis from merkel cell carcinoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978596/
https://www.ncbi.nlm.nih.gov/pubmed/31993571
http://dx.doi.org/10.1016/j.mayocpiqo.2019.09.005
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