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Assessment of Selected Serum Electrolyte and Associated Risk Factors in Diabetic Patients

PURPOSE: The objective of this study was to assess selected serum electrolytes imbalance and associated factors in diabetic patients attending their follow up appointments in Jimma University Medical Center (JUMC) from February 1 to April 1, 2019. PATIENTS AND METHODS: A cross sectional study design...

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Autores principales: Woyesa, Shiferaw Bekele, Gebisa, Waqtola Cheneke, Anshebo, Delebo Lefebo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978677/
https://www.ncbi.nlm.nih.gov/pubmed/32021344
http://dx.doi.org/10.2147/DMSO.S233053
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author Woyesa, Shiferaw Bekele
Gebisa, Waqtola Cheneke
Anshebo, Delebo Lefebo
author_facet Woyesa, Shiferaw Bekele
Gebisa, Waqtola Cheneke
Anshebo, Delebo Lefebo
author_sort Woyesa, Shiferaw Bekele
collection PubMed
description PURPOSE: The objective of this study was to assess selected serum electrolytes imbalance and associated factors in diabetic patients attending their follow up appointments in Jimma University Medical Center (JUMC) from February 1 to April 1, 2019. PATIENTS AND METHODS: A cross sectional study design was used to assess the selected serum electrolytes in diabetic patients attending their follow up appointments at Jimma University Medical Center (JUMC) chronic illness clinic. A convenience sampling technique was used to include 279 diabetic patients in the study and an interviewer based questionnaire was used to include all necessary data from each diabetic patient. Five milliliters of blood were collected from each subject and processed and analyzed for blood glucose and serum electrolyte determination by ABX Pentra400 and Humalyte plus(5) ion-selective electrode (ISE) system  clinical chemistry analyzers. Pearson's correlation coefficient model and multivariate logistic regression were used respectively to assess the correlation and significant association between abnormal serum electrolytes and independent variables. RESULTS: A high prevalence of one or more serum electrolyte abnormalities was determined in diabetic patients. The overall prevalence was 42.0% (n=116/276) in which hyponatremia was the highest followed by hypochloremia and hypercalcemia, 40.6%, 14.9% and 10.9% respectively. Age, type of medication, and high body mass index (BMI) had strong positive correlations with abnormal serum concentration levels of sodium (r=0.611, P=0.731), potassium (r=0.752, P=0.812) and chloride (r=0.645, P=0.459). Being employed (AOR: 3.933, 95% C.I: 1.057–14.637, P value: 0.041), treated with mixed medications (AOR: 2.9, 95% C.I: 1.292–6.441, P value: 0.010) and being unable to control blood glucose level or being hyperglycemic (AOR: 3.2, 95% C.I: 2.179–5.721, P value: 0.000) were statistically identified as risk factors for serum electrolyte abnormalities in diabetic patients. CONCLUSION: The serum electrolyte concentration level was highly abnormal in diabetic patients. The prevalence of abnormal concentration was more common in diabetic patients with advanced age, and some variables had strong positive correlation with abnormal serum electrolyte level in diabetic patients.
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spelling pubmed-69786772020-02-04 Assessment of Selected Serum Electrolyte and Associated Risk Factors in Diabetic Patients Woyesa, Shiferaw Bekele Gebisa, Waqtola Cheneke Anshebo, Delebo Lefebo Diabetes Metab Syndr Obes Original Research PURPOSE: The objective of this study was to assess selected serum electrolytes imbalance and associated factors in diabetic patients attending their follow up appointments in Jimma University Medical Center (JUMC) from February 1 to April 1, 2019. PATIENTS AND METHODS: A cross sectional study design was used to assess the selected serum electrolytes in diabetic patients attending their follow up appointments at Jimma University Medical Center (JUMC) chronic illness clinic. A convenience sampling technique was used to include 279 diabetic patients in the study and an interviewer based questionnaire was used to include all necessary data from each diabetic patient. Five milliliters of blood were collected from each subject and processed and analyzed for blood glucose and serum electrolyte determination by ABX Pentra400 and Humalyte plus(5) ion-selective electrode (ISE) system  clinical chemistry analyzers. Pearson's correlation coefficient model and multivariate logistic regression were used respectively to assess the correlation and significant association between abnormal serum electrolytes and independent variables. RESULTS: A high prevalence of one or more serum electrolyte abnormalities was determined in diabetic patients. The overall prevalence was 42.0% (n=116/276) in which hyponatremia was the highest followed by hypochloremia and hypercalcemia, 40.6%, 14.9% and 10.9% respectively. Age, type of medication, and high body mass index (BMI) had strong positive correlations with abnormal serum concentration levels of sodium (r=0.611, P=0.731), potassium (r=0.752, P=0.812) and chloride (r=0.645, P=0.459). Being employed (AOR: 3.933, 95% C.I: 1.057–14.637, P value: 0.041), treated with mixed medications (AOR: 2.9, 95% C.I: 1.292–6.441, P value: 0.010) and being unable to control blood glucose level or being hyperglycemic (AOR: 3.2, 95% C.I: 2.179–5.721, P value: 0.000) were statistically identified as risk factors for serum electrolyte abnormalities in diabetic patients. CONCLUSION: The serum electrolyte concentration level was highly abnormal in diabetic patients. The prevalence of abnormal concentration was more common in diabetic patients with advanced age, and some variables had strong positive correlation with abnormal serum electrolyte level in diabetic patients. Dove 2019-12-31 /pmc/articles/PMC6978677/ /pubmed/32021344 http://dx.doi.org/10.2147/DMSO.S233053 Text en © 2019 Woyesa et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Woyesa, Shiferaw Bekele
Gebisa, Waqtola Cheneke
Anshebo, Delebo Lefebo
Assessment of Selected Serum Electrolyte and Associated Risk Factors in Diabetic Patients
title Assessment of Selected Serum Electrolyte and Associated Risk Factors in Diabetic Patients
title_full Assessment of Selected Serum Electrolyte and Associated Risk Factors in Diabetic Patients
title_fullStr Assessment of Selected Serum Electrolyte and Associated Risk Factors in Diabetic Patients
title_full_unstemmed Assessment of Selected Serum Electrolyte and Associated Risk Factors in Diabetic Patients
title_short Assessment of Selected Serum Electrolyte and Associated Risk Factors in Diabetic Patients
title_sort assessment of selected serum electrolyte and associated risk factors in diabetic patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978677/
https://www.ncbi.nlm.nih.gov/pubmed/32021344
http://dx.doi.org/10.2147/DMSO.S233053
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