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Exploiting Human NK Cells in Tumor Therapy

NK cells play an important role in the innate defenses against tumor growth and metastases. Human NK cell activation and function are regulated by an array of HLA class I-specific inhibitory receptors and activating receptors recognizing ligands expressed de novo on tumor or virus-infected cells. NK...

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Detalles Bibliográficos
Autores principales: Vacca, Paola, Pietra, Gabriella, Tumino, Nicola, Munari, Enrico, Mingari, Maria Cristina, Moretta, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978749/
https://www.ncbi.nlm.nih.gov/pubmed/32010130
http://dx.doi.org/10.3389/fimmu.2019.03013