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MLH1 promoter hypermethylation in uterine carcinosarcoma rarely coexists with TP53 mutation
INTRODUCTION: Carcinosarcoma (CS) is an infrequent neoplasm composed of a carcinomatous and a sarcomatous element. Its molecular pathogenesis is poorly understood. In this study, we investigated the disturbances in the immunohistochemical expression of p53 and mismatch repair (MMR) proteins, as well...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978758/ https://www.ncbi.nlm.nih.gov/pubmed/31992951 http://dx.doi.org/10.5114/wo.2019.89635 |