Cargando…

MLH1 promoter hypermethylation in uterine carcinosarcoma rarely coexists with TP53 mutation

INTRODUCTION: Carcinosarcoma (CS) is an infrequent neoplasm composed of a carcinomatous and a sarcomatous element. Its molecular pathogenesis is poorly understood. In this study, we investigated the disturbances in the immunohistochemical expression of p53 and mismatch repair (MMR) proteins, as well...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunc, Michal, Gabrych, Anna, Rekawiecki, Bartlomiej, Gorczynski, Adam, Franke, Sabine, Haybaeck, Johannes, Biernat, Wojciech, Czapiewski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978758/
https://www.ncbi.nlm.nih.gov/pubmed/31992951
http://dx.doi.org/10.5114/wo.2019.89635