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Culprit or Bystander: Defective Mitophagy in Alzheimer’s Disease
Mitophagy is a selective engulfment and degradation of damaged mitochondria through the cellular autophagy machinery, a major mechanism responsible for mitochondrial quality control. Increased accumulation of damaged mitochondria in the Alzheimer’s disease (AD) human brain are evident, although unde...
Autores principales: | Xie, Chenglong, Aman, Yahyah, Adriaanse, Bryan A., Cader, M. Zameel, Plun-Favreau, Hélène, Xiao, Jian, Fang, Evandro F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978796/ https://www.ncbi.nlm.nih.gov/pubmed/32010698 http://dx.doi.org/10.3389/fcell.2019.00391 |
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