Direct Quantification of Damaged Nucleotides in Oligonucleotides Using an Aerolysin Single Molecule Interface

[Image: see text] DNA lesions such as metholcytosine((m)C), 8-OXO-guanine ((O)G), inosine (I), etc. could cause genetic diseases. Identification of the varieties of lesion bases are usually beyond the capability of conventional DNA sequencing which is mainly designed to discriminate four bases only....

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Detalles Bibliográficos
Autores principales: Wang, Jiajun, Li, Meng-Yin, Yang, Jie, Wang, Ya-Qian, Wu, Xue-Yuan, Huang, Jin, Ying, Yi-Lun, Long, Yi-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978832/
https://www.ncbi.nlm.nih.gov/pubmed/31989027
http://dx.doi.org/10.1021/acscentsci.9b01129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978832/
https://www.ncbi.nlm.nih.gov/pubmed/31989027
http://dx.doi.org/10.1021/acscentsci.9b01129

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