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Direct Quantification of Damaged Nucleotides in Oligonucleotides Using an Aerolysin Single Molecule Interface
[Image: see text] DNA lesions such as metholcytosine((m)C), 8-OXO-guanine ((O)G), inosine (I), etc. could cause genetic diseases. Identification of the varieties of lesion bases are usually beyond the capability of conventional DNA sequencing which is mainly designed to discriminate four bases only....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978832/ https://www.ncbi.nlm.nih.gov/pubmed/31989027 http://dx.doi.org/10.1021/acscentsci.9b01129 |