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Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate IL-6-induced acute liver injury through miR-455-3p

BACKGROUND: Using a toxin-induced nonhuman primate model of acute liver failure (ALF), we previously reported that peripheral infusion of human umbilical cord mesenchymal stem cells (hUC-MSCs) strongly suppresses the activation of circulating monocytes and interleukin-6 (IL-6) production, thereby di...

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Detalles Bibliográficos
Autores principales: Shao, Mingyang, Xu, Qing, Wu, Zhenru, Chen, Yuwei, Shu, Yuke, Cao, Xiaoyue, Chen, Menglin, Zhang, Bo, Zhou, Yongjie, Yao, Rong, Shi, Yujun, Bu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979401/
https://www.ncbi.nlm.nih.gov/pubmed/31973730
http://dx.doi.org/10.1186/s13287-020-1550-0