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Antioxidant effect of endothelin-1 receptor antagonist protects the rat kidney against chronic injury induced by hypertension and hyperglycemia
Hypertension and Diabetes mellitus are the two main causes of chronic kidney disease that culminate in the final stage of kidney disease. Since these two risk factors are common and can overlap, new approaches to prevent or treat them are needed. Macitentan (MAC) is a new non-selective antagonist of...
Autores principales: | Caires, Agnaldo, Convento, Marcia Bastos, Castino, Bianca, Leme, Ala Moana, Pessoa, Edson de Andrade, Aragão, Alef, Schor, Nestor, Borges, Fernanda Teixeira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Nefrologia
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979570/ https://www.ncbi.nlm.nih.gov/pubmed/31508666 http://dx.doi.org/10.1590/2175-8239-JBN-2018-0162 |
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