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Serum amyloid P component promotes formation of distinct aggregated lysozyme morphologies and reduces toxicity in Drosophila flies expressing F57I lysozyme

Many conflicting reports about the involvement of serum amyloid P component (SAP) in amyloid diseases have been presented over the years; SAP is known to be a universal component of amyloid aggregates but it has been suggested that it can both induce and suppress amyloid formation. By using our Dros...

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Detalles Bibliográficos
Autores principales: Bergkvist, Liza, Richards, Daniel R., Bernardo-Gancedo, Ana, Kumita, Janet R., Nilsson, Peter R., Brorsson, Ann-Christin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980568/
https://www.ncbi.nlm.nih.gov/pubmed/31978114
http://dx.doi.org/10.1371/journal.pone.0227227