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Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration
Prostate embryonic development, pubertal and adult growth, maintenance, and regeneration are regulated through androgen signaling-mediated mesenchymal-epithelial interactions. Specifically, the essential role of mesenchymal androgen signaling in the development of prostate epithelium has been observ...
Autores principales: | Le, Vien, He, Yongfeng, Aldahl, Joseph, Hooker, Erika, Yu, Eun-Jeong, Olson, Adam, Kim, Won Kyung, Lee, Dong-Hoon, Wong, Monica, Sheng, Ruoyu, Mi, Jiaqi, Geradts, Joseph, Cunha, Gerald R., Sun, Zijie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980684/ https://www.ncbi.nlm.nih.gov/pubmed/31929563 http://dx.doi.org/10.1371/journal.pgen.1008588 |
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