Cargando…

Absolute Neutrophil Count Levels among Degree of Differentiation and Tumor Location in Colorectal Cancer Patients in Medan

BACKGROUND: Absolute Neutrophil Count (ANC) recently a derived score composed of white blood cell and has been evaluated in a large number of the malignancy. AIM: The aim of this study was to investigate ANC levels among degree of differentiation and tumor location in Colorectal Cancer (CRC) in Meda...

Descripción completa

Detalles Bibliográficos
Autores principales: Siregar, Gontar Alamsyah, Anshari, Farhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980803/
https://www.ncbi.nlm.nih.gov/pubmed/32002077
http://dx.doi.org/10.3889/oamjms.2019.443
_version_ 1783490992746266624
author Siregar, Gontar Alamsyah
Anshari, Farhan
author_facet Siregar, Gontar Alamsyah
Anshari, Farhan
author_sort Siregar, Gontar Alamsyah
collection PubMed
description BACKGROUND: Absolute Neutrophil Count (ANC) recently a derived score composed of white blood cell and has been evaluated in a large number of the malignancy. AIM: The aim of this study was to investigate ANC levels among degree of differentiation and tumor location in Colorectal Cancer (CRC) in Medan. METHODS: This study was a cross-sectional analytical study on eighty consecutive patients with CRC. Data collection was obtained from the medical record of the patient at Adam Malik General Hospital, Medan, Indonesia. Inclusion criteria were included male or female aged ≥ 18 years old, the patient with CRC, blood test especially ANC, and the patient with histopathology test. The exclusion criteria were defined as a patient with chemotherapy, HIV, and the patient with sepsis. Data were analyzed with SPSS for window version 21. RESULTS: here were Rectal cancer 49.4%, Left side colon cancer 43.2%, and Right-side colon cancer 6.2%. Histopathological findings well differentiated 40.7%, moderate differentiated 32.1%, and poorly differentiated 25.9%. This study showed that no significant differences between ANC and location of the tumor (p = 0.951), but ANC level was significant in histopathological findings (p = 0.0001). CONCLUSION: ANC increased in poorly differentiated, and location of the tumor is left side colon cancer.
format Online
Article
Text
id pubmed-6980803
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Republic of Macedonia
record_format MEDLINE/PubMed
spelling pubmed-69808032020-01-30 Absolute Neutrophil Count Levels among Degree of Differentiation and Tumor Location in Colorectal Cancer Patients in Medan Siregar, Gontar Alamsyah Anshari, Farhan Open Access Maced J Med Sci Tropical and Infectious Diseases Control and Management BACKGROUND: Absolute Neutrophil Count (ANC) recently a derived score composed of white blood cell and has been evaluated in a large number of the malignancy. AIM: The aim of this study was to investigate ANC levels among degree of differentiation and tumor location in Colorectal Cancer (CRC) in Medan. METHODS: This study was a cross-sectional analytical study on eighty consecutive patients with CRC. Data collection was obtained from the medical record of the patient at Adam Malik General Hospital, Medan, Indonesia. Inclusion criteria were included male or female aged ≥ 18 years old, the patient with CRC, blood test especially ANC, and the patient with histopathology test. The exclusion criteria were defined as a patient with chemotherapy, HIV, and the patient with sepsis. Data were analyzed with SPSS for window version 21. RESULTS: here were Rectal cancer 49.4%, Left side colon cancer 43.2%, and Right-side colon cancer 6.2%. Histopathological findings well differentiated 40.7%, moderate differentiated 32.1%, and poorly differentiated 25.9%. This study showed that no significant differences between ANC and location of the tumor (p = 0.951), but ANC level was significant in histopathological findings (p = 0.0001). CONCLUSION: ANC increased in poorly differentiated, and location of the tumor is left side colon cancer. Republic of Macedonia 2019-10-14 /pmc/articles/PMC6980803/ /pubmed/32002077 http://dx.doi.org/10.3889/oamjms.2019.443 Text en Copyright: © 2019 Gontar Alamsyah Siregar, Farhan Anshari. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0)
spellingShingle Tropical and Infectious Diseases Control and Management
Siregar, Gontar Alamsyah
Anshari, Farhan
Absolute Neutrophil Count Levels among Degree of Differentiation and Tumor Location in Colorectal Cancer Patients in Medan
title Absolute Neutrophil Count Levels among Degree of Differentiation and Tumor Location in Colorectal Cancer Patients in Medan
title_full Absolute Neutrophil Count Levels among Degree of Differentiation and Tumor Location in Colorectal Cancer Patients in Medan
title_fullStr Absolute Neutrophil Count Levels among Degree of Differentiation and Tumor Location in Colorectal Cancer Patients in Medan
title_full_unstemmed Absolute Neutrophil Count Levels among Degree of Differentiation and Tumor Location in Colorectal Cancer Patients in Medan
title_short Absolute Neutrophil Count Levels among Degree of Differentiation and Tumor Location in Colorectal Cancer Patients in Medan
title_sort absolute neutrophil count levels among degree of differentiation and tumor location in colorectal cancer patients in medan
topic Tropical and Infectious Diseases Control and Management
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980803/
https://www.ncbi.nlm.nih.gov/pubmed/32002077
http://dx.doi.org/10.3889/oamjms.2019.443
work_keys_str_mv AT siregargontaralamsyah absoluteneutrophilcountlevelsamongdegreeofdifferentiationandtumorlocationincolorectalcancerpatientsinmedan
AT ansharifarhan absoluteneutrophilcountlevelsamongdegreeofdifferentiationandtumorlocationincolorectalcancerpatientsinmedan