Crystal structures of Triosephosphate Isomerases from Taenia solium and Schistosoma mansoni provide insights for vaccine rationale and drug design against helminth parasites

Triosephosphate isomerases (TPIs) from Taenia solium (TsTPI) and Schistosoma mansoni (SmTPI) are potential vaccine and drug targets against cysticercosis and schistosomiasis, respectively. This is due to the dependence of parasitic helminths on glycolysis and because those proteins elicit an immune...

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Detalles Bibliográficos
Autores principales: Jimenez-Sandoval, Pedro, Castro-Torres, Eduardo, González-González, Rogelio, Díaz-Quezada, Corina, Gurrola, Misraim, Camacho-Manriquez, Laura D., Leyva-Navarro, Lucia, Brieba, Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980832/
https://www.ncbi.nlm.nih.gov/pubmed/31923219
http://dx.doi.org/10.1371/journal.pntd.0007815

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