Cargando…
Differences in Psychotropic Drug Prescribing Between Ethnic Groups of People with Dementia in the United Kingdom
PURPOSE: To test hypotheses that minority ethnic people with dementia in the UK receive fewer anti-dementia drugs and more psychotropic and anticholinergic drugs associated with harms. PATIENTS AND METHODS: We analyzed UK primary care electronic health records from The Health Improvement Network (TH...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980848/ https://www.ncbi.nlm.nih.gov/pubmed/32021472 http://dx.doi.org/10.2147/CLEP.S222126 |
_version_ | 1783491003126120448 |
---|---|
author | Jones, Mary Elizabeth Petersen, Irene Walters, Kate Bhanu, Cini Manthorpe, Jill Raine, Rosalind Mukadam, Naaheed Cooper, Claudia |
author_facet | Jones, Mary Elizabeth Petersen, Irene Walters, Kate Bhanu, Cini Manthorpe, Jill Raine, Rosalind Mukadam, Naaheed Cooper, Claudia |
author_sort | Jones, Mary Elizabeth |
collection | PubMed |
description | PURPOSE: To test hypotheses that minority ethnic people with dementia in the UK receive fewer anti-dementia drugs and more psychotropic and anticholinergic drugs associated with harms. PATIENTS AND METHODS: We analyzed UK primary care electronic health records from The Health Improvement Network (THIN) database (2014–2016), comparing psychotropic drug prescribing initiation and duration between people with dementia from White, Black, and Asian ethnic groups. We repeated analyses in people (aged 50+) without dementia, to explore whether any differences found reflected prescribing patterns in the general older population, or were specific to dementia. RESULTS: We included 53,718 people with and 1,648,889 people without dementia. Among people with dementia, compared to White ethnic groups, Asian people were less likely to be prescribed anti-dementia drugs when they were potentially indicated (adjusted prevalence rate ratio 0.86 (95% Confidence Interval 0.76–0.98)), and received them for on average 15 days/year less. Compared to White groups, Asian and Black individuals with dementia were no more likely to take an antipsychotic drug, but those that had were prescribed them for 17 and 27 days/year more, respectively (190.8 (179.6–199.1) and 200.7 (191.1–206.5) days). Black people were less likely to be prescribed anxiolytics/hypnotics (0.60 (0.44–0.8)), but the duration these drugs were prescribed was similar across ethnic groups. Asian people were more likely to be prescribed anticholinergic drugs (1.43 (1.19–1.73)), in analyses unadjusted for cardiovascular comorbidities. Among people without dementia, those in the Asian and Black ethnic groups were less likely to be prescribed psychotropic drugs, relative to people from White groups. CONCLUSION: Among people with dementia, Asian groups received less potentially beneficial symptomatic treatments, and Asian and Black groups were prescribed antipsychotic drugs for longer than White ethnic groups. Our findings may indicate care inequalities. |
format | Online Article Text |
id | pubmed-6980848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-69808482020-02-04 Differences in Psychotropic Drug Prescribing Between Ethnic Groups of People with Dementia in the United Kingdom Jones, Mary Elizabeth Petersen, Irene Walters, Kate Bhanu, Cini Manthorpe, Jill Raine, Rosalind Mukadam, Naaheed Cooper, Claudia Clin Epidemiol Original Research PURPOSE: To test hypotheses that minority ethnic people with dementia in the UK receive fewer anti-dementia drugs and more psychotropic and anticholinergic drugs associated with harms. PATIENTS AND METHODS: We analyzed UK primary care electronic health records from The Health Improvement Network (THIN) database (2014–2016), comparing psychotropic drug prescribing initiation and duration between people with dementia from White, Black, and Asian ethnic groups. We repeated analyses in people (aged 50+) without dementia, to explore whether any differences found reflected prescribing patterns in the general older population, or were specific to dementia. RESULTS: We included 53,718 people with and 1,648,889 people without dementia. Among people with dementia, compared to White ethnic groups, Asian people were less likely to be prescribed anti-dementia drugs when they were potentially indicated (adjusted prevalence rate ratio 0.86 (95% Confidence Interval 0.76–0.98)), and received them for on average 15 days/year less. Compared to White groups, Asian and Black individuals with dementia were no more likely to take an antipsychotic drug, but those that had were prescribed them for 17 and 27 days/year more, respectively (190.8 (179.6–199.1) and 200.7 (191.1–206.5) days). Black people were less likely to be prescribed anxiolytics/hypnotics (0.60 (0.44–0.8)), but the duration these drugs were prescribed was similar across ethnic groups. Asian people were more likely to be prescribed anticholinergic drugs (1.43 (1.19–1.73)), in analyses unadjusted for cardiovascular comorbidities. Among people without dementia, those in the Asian and Black ethnic groups were less likely to be prescribed psychotropic drugs, relative to people from White groups. CONCLUSION: Among people with dementia, Asian groups received less potentially beneficial symptomatic treatments, and Asian and Black groups were prescribed antipsychotic drugs for longer than White ethnic groups. Our findings may indicate care inequalities. Dove 2020-01-20 /pmc/articles/PMC6980848/ /pubmed/32021472 http://dx.doi.org/10.2147/CLEP.S222126 Text en © 2020 Jones et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Jones, Mary Elizabeth Petersen, Irene Walters, Kate Bhanu, Cini Manthorpe, Jill Raine, Rosalind Mukadam, Naaheed Cooper, Claudia Differences in Psychotropic Drug Prescribing Between Ethnic Groups of People with Dementia in the United Kingdom |
title | Differences in Psychotropic Drug Prescribing Between Ethnic Groups of People with Dementia in the United Kingdom |
title_full | Differences in Psychotropic Drug Prescribing Between Ethnic Groups of People with Dementia in the United Kingdom |
title_fullStr | Differences in Psychotropic Drug Prescribing Between Ethnic Groups of People with Dementia in the United Kingdom |
title_full_unstemmed | Differences in Psychotropic Drug Prescribing Between Ethnic Groups of People with Dementia in the United Kingdom |
title_short | Differences in Psychotropic Drug Prescribing Between Ethnic Groups of People with Dementia in the United Kingdom |
title_sort | differences in psychotropic drug prescribing between ethnic groups of people with dementia in the united kingdom |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980848/ https://www.ncbi.nlm.nih.gov/pubmed/32021472 http://dx.doi.org/10.2147/CLEP.S222126 |
work_keys_str_mv | AT jonesmaryelizabeth differencesinpsychotropicdrugprescribingbetweenethnicgroupsofpeoplewithdementiaintheunitedkingdom AT petersenirene differencesinpsychotropicdrugprescribingbetweenethnicgroupsofpeoplewithdementiaintheunitedkingdom AT walterskate differencesinpsychotropicdrugprescribingbetweenethnicgroupsofpeoplewithdementiaintheunitedkingdom AT bhanucini differencesinpsychotropicdrugprescribingbetweenethnicgroupsofpeoplewithdementiaintheunitedkingdom AT manthorpejill differencesinpsychotropicdrugprescribingbetweenethnicgroupsofpeoplewithdementiaintheunitedkingdom AT rainerosalind differencesinpsychotropicdrugprescribingbetweenethnicgroupsofpeoplewithdementiaintheunitedkingdom AT mukadamnaaheed differencesinpsychotropicdrugprescribingbetweenethnicgroupsofpeoplewithdementiaintheunitedkingdom AT cooperclaudia differencesinpsychotropicdrugprescribingbetweenethnicgroupsofpeoplewithdementiaintheunitedkingdom |