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Anticancer activity of dietary xanthone α-mangostin against hepatocellular carcinoma by inhibition of STAT3 signaling via stabilization of SHP1

Hepatocellular carcinoma (HCC) is one of the most lethal human cancers worldwide. The dietary xanthone α-mangostin (α-MGT) exhibits potent anti-tumor effects in vitro and in vivo. However, the anti-HCC effects of α-MGT and their underlying mechanisms are still vague. Aberrant activation of signal tr...

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Detalles Bibliográficos
Autores principales:	Zhang, Hai, Tan, Yu-ping, Zhao, Lin, Wang, Lun, Fu, Nai-jie, Zheng, Song-ping, Shen, Xiao-fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981176/ https://www.ncbi.nlm.nih.gov/pubmed/31980595 http://dx.doi.org/10.1038/s41419-020-2227-4

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