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Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing
The humanization of animal model immune systems by genetic engineering has shown great promise for antibody discovery, tolerance studies and for the evaluation of vaccines. Assessment of the baseline antibody repertoires of unimmunized model animals will be useful as a benchmark for future immunizat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981180/ https://www.ncbi.nlm.nih.gov/pubmed/31980672 http://dx.doi.org/10.1038/s41598-020-57764-7 |