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YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells

Fibroblastic reticular cells (FRCs) are immunologically specialized myofibroblasts of lymphoid organ, and FRC maturation is essential for structural and functional properties of lymph nodes (LNs). Here we show that YAP and TAZ (YAP/TAZ), the final effectors of Hippo signaling, regulate FRC commitmen...

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Detalles Bibliográficos
Autores principales: Choi, Sung Yong, Bae, Hosung, Jeong, Sun-Hye, Park, Intae, Cho, Hyunsoo, Hong, Seon Pyo, Lee, Da-Hye, Lee, Choong-kun, Park, Jin-Sung, Suh, Sang Heon, Choi, Jeongwoon, Yang, Myung Jin, Jang, Jeon Yeob, Onder, Lucas, Moon, Jeong Hwan, Jeong, Han-Sin, Adams, Ralf H., Kim, Jin-Man, Ludewig, Burkhard, Song, Joo-Hye, Lim, Dae-Sik, Koh, Gou Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981200/
https://www.ncbi.nlm.nih.gov/pubmed/31980640
http://dx.doi.org/10.1038/s41467-020-14293-1