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Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin

Centromeres are defined by a self-propagating chromatin structure based on stable inheritance of CENP-A containing nucleosomes. Here, we present a genetic screen coupled to pulse-chase labeling that allow us to identify proteins selectively involved in deposition of nascent CENP-A or in long-term tr...

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Detalles Bibliográficos
Autores principales: Mitra, Sreyoshi, Bodor, Dani L., David, Ana F., Abdul-Zani, Izma, Mata, João F., Neumann, Beate, Reither, Sabine, Tischer, Christian, Jansen, Lars E. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981222/
https://www.ncbi.nlm.nih.gov/pubmed/31980633
http://dx.doi.org/10.1038/s41467-019-14276-x