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Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin
Centromeres are defined by a self-propagating chromatin structure based on stable inheritance of CENP-A containing nucleosomes. Here, we present a genetic screen coupled to pulse-chase labeling that allow us to identify proteins selectively involved in deposition of nascent CENP-A or in long-term tr...
Autores principales: | Mitra, Sreyoshi, Bodor, Dani L., David, Ana F., Abdul-Zani, Izma, Mata, João F., Neumann, Beate, Reither, Sabine, Tischer, Christian, Jansen, Lars E. T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981222/ https://www.ncbi.nlm.nih.gov/pubmed/31980633 http://dx.doi.org/10.1038/s41467-019-14276-x |
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