Increased intestinal permeability exacerbates sepsis through reduced hepatic SCD-1 activity and dysregulated iron recycling

Inflammatory bowel disease is associated with changes in the mucosal barrier, increased intestinal permeability, and increased risk of infections and sepsis, but the underlying mechanisms are incompletely understood. Here, we show how continuous translocation of gut microbial components affects iron...

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Detalles Bibliográficos
Autores principales: Kumar, Manish, Leon Coria, Aralia, Cornick, Steve, Petri, Björn, Mayengbam, Shyamchand, Jijon, Humberto B., Moreau, France, Shearer, Jane, Chadee, Kris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981269/
https://www.ncbi.nlm.nih.gov/pubmed/31980623
http://dx.doi.org/10.1038/s41467-019-14182-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981269/
https://www.ncbi.nlm.nih.gov/pubmed/31980623
http://dx.doi.org/10.1038/s41467-019-14182-2

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