Whole genome sequencing of orofacial cleft trios from the Gabriella Miller Kids First Pediatric Research Consortium identifies a new locus on chromosome 21

Orofacial clefts (OFCs) are among the most prevalent craniofacial birth defects worldwide and create a significant public health burden. The majority of OFCs are non-syndromic, and the genetic etiology of non-syndromic OFCs is only partially determined. Here, we analyze whole genome sequence (WGS) d...

Descripción completa

Detalles Bibliográficos
Autores principales: Mukhopadhyay, Nandita, Bishop, Madison, Mortillo, Michael, Chopra, Pankaj, Hetmanski, Jacqueline B., Taub, Margaret A., Moreno, Lina M., Valencia-Ramirez, Luz Consuelo, Restrepo, Claudia, Wehby, George L., Hecht, Jacqueline T., Deleyiannis, Frederic, Butali, Azeez, Weinberg, Seth M., Beaty, Terri H., Murray, Jeffrey C., Leslie, Elizabeth J., Feingold, Eleanor, Marazita, Mary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981325/
https://www.ncbi.nlm.nih.gov/pubmed/31848685
http://dx.doi.org/10.1007/s00439-019-02099-1

Ejemplares similares

Ejemplares similares