The Selective Class IIa Histone Deacetylase Inhibitor TMP195 Resensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs

Multidrug resistance caused by the overexpression of the ATP-binding cassette (ABC) proteins in cancer cells remains one of the most difficult challenges faced by drug developers and clinical scientists. The emergence of multidrug-resistant cancers has driven efforts from researchers to develop inno...

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Detalles Bibliográficos
Autores principales: Wu, Chung-Pu, Lusvarghi, Sabrina, Wang, Jyun-Cheng, Hsiao, Sung-Han, Huang, Yang-Hui, Hung, Tai-Ho, Ambudkar, Suresh V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981391/
https://www.ncbi.nlm.nih.gov/pubmed/31905792
http://dx.doi.org/10.3390/ijms21010238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981391/
https://www.ncbi.nlm.nih.gov/pubmed/31905792
http://dx.doi.org/10.3390/ijms21010238

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