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The Selective Class IIa Histone Deacetylase Inhibitor TMP195 Resensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs
Multidrug resistance caused by the overexpression of the ATP-binding cassette (ABC) proteins in cancer cells remains one of the most difficult challenges faced by drug developers and clinical scientists. The emergence of multidrug-resistant cancers has driven efforts from researchers to develop inno...
Autores principales: | Wu, Chung-Pu, Lusvarghi, Sabrina, Wang, Jyun-Cheng, Hsiao, Sung-Han, Huang, Yang-Hui, Hung, Tai-Ho, Ambudkar, Suresh V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981391/ https://www.ncbi.nlm.nih.gov/pubmed/31905792 http://dx.doi.org/10.3390/ijms21010238 |
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