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Differences in Stability of Viral and Viral-Cellular Fusion Transcripts in HPV-Induced Cervical Cancers

HPV-DNA integration results in dysregulation of viral oncogene expression. Because viral-cellular fusion transcripts inherently lack the viral AU-rich elements of the 3’UTR, they are considered to be more stable than episome-derived transcripts. The aim of this study is to provide formal proof for t...

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Detalles Bibliográficos
Autores principales: Ehrig, Franziska, Häfner, Norman, Driesch, Corina, Kraus Christiansen, Irene, Beer, Katrin, Schmitz, Martina, Runnebaum, Ingo B., Dürst, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981427/
https://www.ncbi.nlm.nih.gov/pubmed/31877944
http://dx.doi.org/10.3390/ijms21010112