Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain

Extracellular vesicles (EVs) derived from human bone marrow mesenchymal stem cells (hMSCs) have great promise as biologics to treat neurological and neurodegenerative conditions due to their robust antiinflammatory and neuroprotective properties. Besides, intranasal (IN) administration of EVs has ca...

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Detalles Bibliográficos
Autores principales: Kodali, Maheedhar, Castro, Olagide W., Kim, Dong-Ki, Thomas, Alicia, Shuai, Bing, Attaluri, Sahithi, Upadhya, Raghavendra, Gitai, Daniel, Madhu, Leelavathi N., Prockop, Darwin J., Shetty, Ashok K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981466/
https://www.ncbi.nlm.nih.gov/pubmed/31888012
http://dx.doi.org/10.3390/ijms21010181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981466/
https://www.ncbi.nlm.nih.gov/pubmed/31888012
http://dx.doi.org/10.3390/ijms21010181

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