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Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain
Extracellular vesicles (EVs) derived from human bone marrow mesenchymal stem cells (hMSCs) have great promise as biologics to treat neurological and neurodegenerative conditions due to their robust antiinflammatory and neuroprotective properties. Besides, intranasal (IN) administration of EVs has ca...
Autores principales: | Kodali, Maheedhar, Castro, Olagide W., Kim, Dong-Ki, Thomas, Alicia, Shuai, Bing, Attaluri, Sahithi, Upadhya, Raghavendra, Gitai, Daniel, Madhu, Leelavathi N., Prockop, Darwin J., Shetty, Ashok K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981466/ https://www.ncbi.nlm.nih.gov/pubmed/31888012 http://dx.doi.org/10.3390/ijms21010181 |
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