Phosphorylation Signaling in APP Processing in Alzheimer’s Disease

The abnormal accumulation of amyloid-β (Aβ) in the central nervous system is a hallmark of Alzheimer’s disease (AD). The regulation of the processing of the single- transmembrane amyloid precursor protein (APP) plays an important role in the generation of Aβ in the brain. The phosphorylation of APP...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Chen, Dongmei, Lee, Tae Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981488/
https://www.ncbi.nlm.nih.gov/pubmed/31892243
http://dx.doi.org/10.3390/ijms21010209

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