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Ipragliflozin Ameliorates Endoplasmic Reticulum Stress and Apoptosis through Preventing Ectopic Lipid Deposition in Renal Tubules
Background: Chronic kidney disease (CKD) and non-alcoholic steatohepatitis (NASH) are major health burdens closely related to metabolic syndrome. A link between CKD and NASH has been assumed; however, the underlying mechanism is still unknown. Ectopic lipid deposition (ELD) in the hepatocyte results...
Autores principales: | Hosokawa, Kohshiro, Takata, Tomoaki, Sugihara, Takaaki, Matono, Tomomitsu, Koda, Masahiko, Kanda, Tsutomu, Taniguchi, Sosuke, Ida, Ayami, Mae, Yukari, Yamamoto, Marie, Iyama, Takuji, Fukuda, Satoko, Isomoto, Hajime |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981520/ https://www.ncbi.nlm.nih.gov/pubmed/31888083 http://dx.doi.org/10.3390/ijms21010190 |
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