Folding Rate Optimization Promotes Frustrated Interactions in Entangled Protein Structures

Many native structures of proteins accomodate complex topological motifs such as knots, lassos, and other geometrical entanglements. How proteins can fold quickly even in the presence of such topological obstacles is a debated question in structural biology. Recently, the hypothesis that energetic f...

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Detalles Bibliográficos
Autores principales: Norbiato, Federico, Seno, Flavio, Trovato, Antonio, Baiesi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981561/
https://www.ncbi.nlm.nih.gov/pubmed/31892272
http://dx.doi.org/10.3390/ijms21010213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981561/
https://www.ncbi.nlm.nih.gov/pubmed/31892272
http://dx.doi.org/10.3390/ijms21010213

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