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Folding Rate Optimization Promotes Frustrated Interactions in Entangled Protein Structures
Many native structures of proteins accomodate complex topological motifs such as knots, lassos, and other geometrical entanglements. How proteins can fold quickly even in the presence of such topological obstacles is a debated question in structural biology. Recently, the hypothesis that energetic f...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981561/ https://www.ncbi.nlm.nih.gov/pubmed/31892272 http://dx.doi.org/10.3390/ijms21010213 |