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Lixivaptan, a New Generation Diuretic, Counteracts Vasopressin-Induced Aquaporin-2 Trafficking and Function in Renal Collecting Duct Cells

Vasopressin V2 receptor (V2R) antagonists (vaptans) are a new generation of diuretics. Compared with classical diuretics, vaptans promote the excretion of retained body water in disorders in which plasma vasopressin concentrations are inappropriately high for any given plasma osmolality. Under these...

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Detalles Bibliográficos
Autores principales: Di Mise, Annarita, Venneri, Maria, Ranieri, Marianna, Centrone, Mariangela, Pellegrini, Lorenzo, Tamma, Grazia, Valenti, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981680/
https://www.ncbi.nlm.nih.gov/pubmed/31888044
http://dx.doi.org/10.3390/ijms21010183

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