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Lixivaptan, a New Generation Diuretic, Counteracts Vasopressin-Induced Aquaporin-2 Trafficking and Function in Renal Collecting Duct Cells
Vasopressin V2 receptor (V2R) antagonists (vaptans) are a new generation of diuretics. Compared with classical diuretics, vaptans promote the excretion of retained body water in disorders in which plasma vasopressin concentrations are inappropriately high for any given plasma osmolality. Under these...
Autores principales: | Di Mise, Annarita, Venneri, Maria, Ranieri, Marianna, Centrone, Mariangela, Pellegrini, Lorenzo, Tamma, Grazia, Valenti, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981680/ https://www.ncbi.nlm.nih.gov/pubmed/31888044 http://dx.doi.org/10.3390/ijms21010183 |
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