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High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer
DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC). Its DNA amplification is often part of the targeted DNA-sequencing p...
Autores principales: | Katsuta, Eriko, Yan, Li, Takeshita, Takashi, McDonald, Kerry-Ann, Dasgupta, Subhamoy, Opyrchal, Mateusz, Takabe, Kazuaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981812/ https://www.ncbi.nlm.nih.gov/pubmed/31905596 http://dx.doi.org/10.3390/ijms21010217 |
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