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Inhibition of Protein Prenylation of GTPases Alters Endothelial Barrier Function
The members of Rho family of GTPases, RhoA and Rac1 regulate endothelial cytoskeleton dynamics and hence barrier integrity. The spatial activities of these GTPases are regulated by post-translational prenylation. In the present study, we investigated the effect of prenylation inhibition on the endot...
Autores principales: | Aslam, Muhammad, Troidl, Christian, Tanislav, Christian, Rohrbach, Susanne, Gündüz, Dursun, Hamm, Christian W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981884/ https://www.ncbi.nlm.nih.gov/pubmed/31861297 http://dx.doi.org/10.3390/ijms21010002 |
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