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Regulation of the p53 Family Proteins by the Ubiquitin Proteasomal Pathway
The tumor suppressor p53 and its homologues, p63 and p73, play a pivotal role in the regulation of the DNA damage response, cellular homeostasis, development, aging, and metabolism. A number of mouse studies have shown that a genetic defect in the p53 family could lead to spontaneous tumor developme...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981958/ https://www.ncbi.nlm.nih.gov/pubmed/31905981 http://dx.doi.org/10.3390/ijms21010261 |