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Feedback Regulation of Syk by Protein Kinase C in Human Platelets

The spleen tyrosine kinase (Syk) is essential for immunoreceptor tyrosine-based activation motif (ITAM)-dependent platelet activation, and it is stimulated by Src-family kinase (SFK)-/Syk-mediated phosphorylation of Y352 (interdomain-B) and Y525/526 (kinase domain). Additional sites for Syk phosphor...

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Detalles Bibliográficos
Autores principales:	Makhoul, Stephanie, Dorschel, Stephanie, Gambaryan, Stepan, Walter, Ulrich, Jurk, Kerstin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981976/ https://www.ncbi.nlm.nih.gov/pubmed/31881809 http://dx.doi.org/10.3390/ijms21010176

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