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Autophagy Deficiency in Renal Proximal Tubular Cells Leads to an Increase in Cellular Injury and Apoptosis under Normal Fed Conditions

Renal proximal tubular epithelial cells are significantly damaged during acute kidney injury. Renal proximal tubular cell-specific autophagy-deficient mice show increased sensitivity against renal injury, while showing few pathological defects under normal fed conditions. Considering that autophagy...

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Detalles Bibliográficos
Autores principales: Suzuki, Chigure, Tanida, Isei, Oliva Trejo, Juan Alejandro, Kakuta, Soichiro, Uchiyama, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982095/
https://www.ncbi.nlm.nih.gov/pubmed/31881660
http://dx.doi.org/10.3390/ijms21010155

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