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GTP Binding Is Necessary for the Activation of a Toxic Mutant Isoform of the Essential GTPase ObgE

Even though the Obg protein is essential for bacterial viability, the cellular functions of this universally conserved GTPase remain enigmatic. Moreover, the influence of GTP and GDP binding on the activity of this protein is largely unknown. Previously, we identified a mutant isoform of ObgE (the O...

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Detalles Bibliográficos
Autores principales: Dewachter, Liselot, Deckers, Babette, Martin, Ella, Herpels, Pauline, Gkekas, Sotirios, Versées, Wim, Verstraeten, Natalie, Fauvart, Maarten, Michiels, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982127/
https://www.ncbi.nlm.nih.gov/pubmed/31861427
http://dx.doi.org/10.3390/ijms21010016