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The Effect of Proline cis-trans Isomerization on the Folding of the C-Terminal SH2 Domain from p85

SH2 domains are protein domains that modulate protein–protein interactions through a specific interaction with sequences containing phosphorylated tyrosines. In this work, we analyze the folding pathway of the C-terminal SH2 domain of the p85 regulatory subunit of the protein PI3K, which presents a...

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Detalles Bibliográficos
Autores principales:	Troilo, Francesca, Malagrinò, Francesca, Visconti, Lorenzo, Toto, Angelo, Gianni, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982175/ https://www.ncbi.nlm.nih.gov/pubmed/31878075 http://dx.doi.org/10.3390/ijms21010125

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