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α-Cyclodextrin-Based Polypseudorotaxane Hydrogels

Supramolecular hydrogels that are based on inclusion complexes between α-cyclodextrin and (co)polymers have gained significant attention over the last decade. They are formed via dynamic noncovalent bonds, such as host–guest interactions and hydrogen bonds, between various building blocks. In contra...

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Autores principales: Domiński, Adrian, Konieczny, Tomasz, Kurcok, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982288/
https://www.ncbi.nlm.nih.gov/pubmed/31905603
http://dx.doi.org/10.3390/ma13010133
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author Domiński, Adrian
Konieczny, Tomasz
Kurcok, Piotr
author_facet Domiński, Adrian
Konieczny, Tomasz
Kurcok, Piotr
author_sort Domiński, Adrian
collection PubMed
description Supramolecular hydrogels that are based on inclusion complexes between α-cyclodextrin and (co)polymers have gained significant attention over the last decade. They are formed via dynamic noncovalent bonds, such as host–guest interactions and hydrogen bonds, between various building blocks. In contrast to typical chemical crosslinking (covalent linkages), supramolecular crosslinking is a type of physical interaction that is characterized by great flexibility and it can be used with ease to create a variety of “smart” hydrogels. Supramolecular hydrogels based on the self-assembly of polypseudorotaxanes formed by a polymer chain “guest” and α-cyclodextrin “host” are promising materials for a wide range of applications. α-cyclodextrin-based polypseudorotaxane hydrogels are an attractive platform for engineering novel functional materials due to their excellent biocompatibility, thixotropic nature, and reversible and stimuli-responsiveness properties. The aim of this review is to provide an overview of the current progress in the chemistry and methods of designing and creating α-cyclodextrin-based supramolecular polypseudorotaxane hydrogels. In the described systems, the guests are (co)polymer chains with various architectures or polymeric nanoparticles. The potential applications of such supramolecular hydrogels are also described.
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spelling pubmed-69822882020-02-07 α-Cyclodextrin-Based Polypseudorotaxane Hydrogels Domiński, Adrian Konieczny, Tomasz Kurcok, Piotr Materials (Basel) Review Supramolecular hydrogels that are based on inclusion complexes between α-cyclodextrin and (co)polymers have gained significant attention over the last decade. They are formed via dynamic noncovalent bonds, such as host–guest interactions and hydrogen bonds, between various building blocks. In contrast to typical chemical crosslinking (covalent linkages), supramolecular crosslinking is a type of physical interaction that is characterized by great flexibility and it can be used with ease to create a variety of “smart” hydrogels. Supramolecular hydrogels based on the self-assembly of polypseudorotaxanes formed by a polymer chain “guest” and α-cyclodextrin “host” are promising materials for a wide range of applications. α-cyclodextrin-based polypseudorotaxane hydrogels are an attractive platform for engineering novel functional materials due to their excellent biocompatibility, thixotropic nature, and reversible and stimuli-responsiveness properties. The aim of this review is to provide an overview of the current progress in the chemistry and methods of designing and creating α-cyclodextrin-based supramolecular polypseudorotaxane hydrogels. In the described systems, the guests are (co)polymer chains with various architectures or polymeric nanoparticles. The potential applications of such supramolecular hydrogels are also described. MDPI 2019-12-28 /pmc/articles/PMC6982288/ /pubmed/31905603 http://dx.doi.org/10.3390/ma13010133 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Domiński, Adrian
Konieczny, Tomasz
Kurcok, Piotr
α-Cyclodextrin-Based Polypseudorotaxane Hydrogels
title α-Cyclodextrin-Based Polypseudorotaxane Hydrogels
title_full α-Cyclodextrin-Based Polypseudorotaxane Hydrogels
title_fullStr α-Cyclodextrin-Based Polypseudorotaxane Hydrogels
title_full_unstemmed α-Cyclodextrin-Based Polypseudorotaxane Hydrogels
title_short α-Cyclodextrin-Based Polypseudorotaxane Hydrogels
title_sort α-cyclodextrin-based polypseudorotaxane hydrogels
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982288/
https://www.ncbi.nlm.nih.gov/pubmed/31905603
http://dx.doi.org/10.3390/ma13010133
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