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α-Cyclodextrin-Based Polypseudorotaxane Hydrogels
Supramolecular hydrogels that are based on inclusion complexes between α-cyclodextrin and (co)polymers have gained significant attention over the last decade. They are formed via dynamic noncovalent bonds, such as host–guest interactions and hydrogen bonds, between various building blocks. In contra...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982288/ https://www.ncbi.nlm.nih.gov/pubmed/31905603 http://dx.doi.org/10.3390/ma13010133 |
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author | Domiński, Adrian Konieczny, Tomasz Kurcok, Piotr |
author_facet | Domiński, Adrian Konieczny, Tomasz Kurcok, Piotr |
author_sort | Domiński, Adrian |
collection | PubMed |
description | Supramolecular hydrogels that are based on inclusion complexes between α-cyclodextrin and (co)polymers have gained significant attention over the last decade. They are formed via dynamic noncovalent bonds, such as host–guest interactions and hydrogen bonds, between various building blocks. In contrast to typical chemical crosslinking (covalent linkages), supramolecular crosslinking is a type of physical interaction that is characterized by great flexibility and it can be used with ease to create a variety of “smart” hydrogels. Supramolecular hydrogels based on the self-assembly of polypseudorotaxanes formed by a polymer chain “guest” and α-cyclodextrin “host” are promising materials for a wide range of applications. α-cyclodextrin-based polypseudorotaxane hydrogels are an attractive platform for engineering novel functional materials due to their excellent biocompatibility, thixotropic nature, and reversible and stimuli-responsiveness properties. The aim of this review is to provide an overview of the current progress in the chemistry and methods of designing and creating α-cyclodextrin-based supramolecular polypseudorotaxane hydrogels. In the described systems, the guests are (co)polymer chains with various architectures or polymeric nanoparticles. The potential applications of such supramolecular hydrogels are also described. |
format | Online Article Text |
id | pubmed-6982288 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-69822882020-02-07 α-Cyclodextrin-Based Polypseudorotaxane Hydrogels Domiński, Adrian Konieczny, Tomasz Kurcok, Piotr Materials (Basel) Review Supramolecular hydrogels that are based on inclusion complexes between α-cyclodextrin and (co)polymers have gained significant attention over the last decade. They are formed via dynamic noncovalent bonds, such as host–guest interactions and hydrogen bonds, between various building blocks. In contrast to typical chemical crosslinking (covalent linkages), supramolecular crosslinking is a type of physical interaction that is characterized by great flexibility and it can be used with ease to create a variety of “smart” hydrogels. Supramolecular hydrogels based on the self-assembly of polypseudorotaxanes formed by a polymer chain “guest” and α-cyclodextrin “host” are promising materials for a wide range of applications. α-cyclodextrin-based polypseudorotaxane hydrogels are an attractive platform for engineering novel functional materials due to their excellent biocompatibility, thixotropic nature, and reversible and stimuli-responsiveness properties. The aim of this review is to provide an overview of the current progress in the chemistry and methods of designing and creating α-cyclodextrin-based supramolecular polypseudorotaxane hydrogels. In the described systems, the guests are (co)polymer chains with various architectures or polymeric nanoparticles. The potential applications of such supramolecular hydrogels are also described. MDPI 2019-12-28 /pmc/articles/PMC6982288/ /pubmed/31905603 http://dx.doi.org/10.3390/ma13010133 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Domiński, Adrian Konieczny, Tomasz Kurcok, Piotr α-Cyclodextrin-Based Polypseudorotaxane Hydrogels |
title | α-Cyclodextrin-Based Polypseudorotaxane Hydrogels |
title_full | α-Cyclodextrin-Based Polypseudorotaxane Hydrogels |
title_fullStr | α-Cyclodextrin-Based Polypseudorotaxane Hydrogels |
title_full_unstemmed | α-Cyclodextrin-Based Polypseudorotaxane Hydrogels |
title_short | α-Cyclodextrin-Based Polypseudorotaxane Hydrogels |
title_sort | α-cyclodextrin-based polypseudorotaxane hydrogels |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982288/ https://www.ncbi.nlm.nih.gov/pubmed/31905603 http://dx.doi.org/10.3390/ma13010133 |
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