Interaction of Nuclear Receptor Subfamily 4 Group A Member 1 (Nr4a1) and Liver Linase B1 (LKB1) Mitigates Type 2 Diabetes Mellitus by Activating Monophosphate-Activated Protein Kinase (AMPK)/Sirtuin 1 (SIRT1) Axis and Inhibiting Nuclear Factor-kappa B (NF-κB) Activation

BACKGROUND: Nuclear receptor subfamily 4 group A member 1 (Nr4a1) has been increasingly investigated in association with type 2 diabetes mellitus (T2DM). This study aimed to explore its efficacy with liver kinase B1 (LKB1) and potential signaling pathways in T2DM. MATERIAL/METHODS: A T2DM model in r...

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Detalles Bibliográficos
Autores principales: Ming, Yi, Yin, Youmin, Sun, Zhaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982402/
https://www.ncbi.nlm.nih.gov/pubmed/31939452
http://dx.doi.org/10.12659/MSM.920278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982402/
https://www.ncbi.nlm.nih.gov/pubmed/31939452
http://dx.doi.org/10.12659/MSM.920278

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