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Modifying ICCA with Trp-Phe-Phe to Enhance in vivo Activity and Form Nano-Medicine
BACKGROUND: 1-(4-isopropylphenyl)-β-carboline-3-carboxylic acid (ICCA) was modified by Trp-Phe-Phe to form 1-(4-isopropylphenyl)-β-carboline-3-carbonyl-Trp-Phe-Phe (ICCA-WFF). PURPOSE: The object of preparing ICCA-WFF was to enhance the in vivo efficacy of ICCA, to explore the possible targeting act...
Autores principales: | Zhang, Xiaoyi, Zhang, Yixin, Wang, Yaonan, Wu, Jianhui, Chen, Haiyan, Zhao, Ming, Peng, Shiqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982437/ https://www.ncbi.nlm.nih.gov/pubmed/32021191 http://dx.doi.org/10.2147/IJN.S229856 |
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