Multiple myeloma with clivus involvement, neurological symptoms, and 45 g/L proteinorachia

The mechanical obstruction of cerebrospinal fluid (CSF) flow can lead to very high hyperproteinorachia. In myeloma, tumoral clivus obstruction can cause such high proteinorachia, associated with paraprotein detection in the CSF in absence of intrathecal synthesis.

Detalles Bibliográficos
Autores principales: Chantran, Yannick, Lavillegrand, Jean‐Rémi, Lefrere, Bertrand, Gaillet, Antoine, Aucouturier, Pierre, Garderet, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982496/
https://www.ncbi.nlm.nih.gov/pubmed/31998476
http://dx.doi.org/10.1002/ccr3.2404
Descripción
Sumario:The mechanical obstruction of cerebrospinal fluid (CSF) flow can lead to very high hyperproteinorachia. In myeloma, tumoral clivus obstruction can cause such high proteinorachia, associated with paraprotein detection in the CSF in absence of intrathecal synthesis.

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