Cargando…

Multiple myeloma with clivus involvement, neurological symptoms, and 45 g/L proteinorachia

The mechanical obstruction of cerebrospinal fluid (CSF) flow can lead to very high hyperproteinorachia. In myeloma, tumoral clivus obstruction can cause such high proteinorachia, associated with paraprotein detection in the CSF in absence of intrathecal synthesis.

Detalles Bibliográficos
Autores principales: Chantran, Yannick, Lavillegrand, Jean‐Rémi, Lefrere, Bertrand, Gaillet, Antoine, Aucouturier, Pierre, Garderet, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982496/
https://www.ncbi.nlm.nih.gov/pubmed/31998476
http://dx.doi.org/10.1002/ccr3.2404
_version_ 1783491323233304576
author Chantran, Yannick
Lavillegrand, Jean‐Rémi
Lefrere, Bertrand
Gaillet, Antoine
Aucouturier, Pierre
Garderet, Laurent
author_facet Chantran, Yannick
Lavillegrand, Jean‐Rémi
Lefrere, Bertrand
Gaillet, Antoine
Aucouturier, Pierre
Garderet, Laurent
author_sort Chantran, Yannick
collection PubMed
description The mechanical obstruction of cerebrospinal fluid (CSF) flow can lead to very high hyperproteinorachia. In myeloma, tumoral clivus obstruction can cause such high proteinorachia, associated with paraprotein detection in the CSF in absence of intrathecal synthesis.
format Online
Article
Text
id pubmed-6982496
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-69824962020-01-29 Multiple myeloma with clivus involvement, neurological symptoms, and 45 g/L proteinorachia Chantran, Yannick Lavillegrand, Jean‐Rémi Lefrere, Bertrand Gaillet, Antoine Aucouturier, Pierre Garderet, Laurent Clin Case Rep Case Reports The mechanical obstruction of cerebrospinal fluid (CSF) flow can lead to very high hyperproteinorachia. In myeloma, tumoral clivus obstruction can cause such high proteinorachia, associated with paraprotein detection in the CSF in absence of intrathecal synthesis. John Wiley and Sons Inc. 2019-09-30 /pmc/articles/PMC6982496/ /pubmed/31998476 http://dx.doi.org/10.1002/ccr3.2404 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Chantran, Yannick
Lavillegrand, Jean‐Rémi
Lefrere, Bertrand
Gaillet, Antoine
Aucouturier, Pierre
Garderet, Laurent
Multiple myeloma with clivus involvement, neurological symptoms, and 45 g/L proteinorachia
title Multiple myeloma with clivus involvement, neurological symptoms, and 45 g/L proteinorachia
title_full Multiple myeloma with clivus involvement, neurological symptoms, and 45 g/L proteinorachia
title_fullStr Multiple myeloma with clivus involvement, neurological symptoms, and 45 g/L proteinorachia
title_full_unstemmed Multiple myeloma with clivus involvement, neurological symptoms, and 45 g/L proteinorachia
title_short Multiple myeloma with clivus involvement, neurological symptoms, and 45 g/L proteinorachia
title_sort multiple myeloma with clivus involvement, neurological symptoms, and 45 g/l proteinorachia
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982496/
https://www.ncbi.nlm.nih.gov/pubmed/31998476
http://dx.doi.org/10.1002/ccr3.2404
work_keys_str_mv AT chantranyannick multiplemyelomawithclivusinvolvementneurologicalsymptomsand45glproteinorachia
AT lavillegrandjeanremi multiplemyelomawithclivusinvolvementneurologicalsymptomsand45glproteinorachia
AT lefrerebertrand multiplemyelomawithclivusinvolvementneurologicalsymptomsand45glproteinorachia
AT gailletantoine multiplemyelomawithclivusinvolvementneurologicalsymptomsand45glproteinorachia
AT aucouturierpierre multiplemyelomawithclivusinvolvementneurologicalsymptomsand45glproteinorachia
AT garderetlaurent multiplemyelomawithclivusinvolvementneurologicalsymptomsand45glproteinorachia