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Correlation Between Lipid Profile and Acne Vulgaris

BACKGROUND AND AIM: Acne is a common skin disease resulting from a complex interaction of various pathogenetic factors. The aim of this study was to find out lipid profile abnormalities in acne vulgaris patients. MATERIAL AND METHODS: This descriptive analytic cross-sectional study was conducted on...

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Autores principales: Sobhan, Mohammadreza, Seif Rabiei, Mohammad Ali, Amerifar, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982527/
https://www.ncbi.nlm.nih.gov/pubmed/32021370
http://dx.doi.org/10.2147/CCID.S230617
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author Sobhan, Mohammadreza
Seif Rabiei, Mohammad Ali
Amerifar, Maryam
author_facet Sobhan, Mohammadreza
Seif Rabiei, Mohammad Ali
Amerifar, Maryam
author_sort Sobhan, Mohammadreza
collection PubMed
description BACKGROUND AND AIM: Acne is a common skin disease resulting from a complex interaction of various pathogenetic factors. The aim of this study was to find out lipid profile abnormalities in acne vulgaris patients. MATERIAL AND METHODS: This descriptive analytic cross-sectional study was conducted on 45 acne patients and 45 age- and sex-matched healthy controls to assess plasma total cholesterol (TC), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride (TG) levels. RESULTS: We showed a higher cholesterol level in acne patients (P=0.025), particularly in men (P=0.04). Other plasma lipids including TG, LDL, and HDL in male and female patients were higher compared to controls, but this is not statistically significant. DISCUSSION AND CONCLUSION: In conclusion, lipid profile was altered in our patients, with high cholesterol level as the commonest derangement, particularly in men. Therefore, screening for lipid profile abnormalities could be considered in the treatment of acne patients.
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spelling pubmed-69825272020-02-04 Correlation Between Lipid Profile and Acne Vulgaris Sobhan, Mohammadreza Seif Rabiei, Mohammad Ali Amerifar, Maryam Clin Cosmet Investig Dermatol Original Research BACKGROUND AND AIM: Acne is a common skin disease resulting from a complex interaction of various pathogenetic factors. The aim of this study was to find out lipid profile abnormalities in acne vulgaris patients. MATERIAL AND METHODS: This descriptive analytic cross-sectional study was conducted on 45 acne patients and 45 age- and sex-matched healthy controls to assess plasma total cholesterol (TC), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride (TG) levels. RESULTS: We showed a higher cholesterol level in acne patients (P=0.025), particularly in men (P=0.04). Other plasma lipids including TG, LDL, and HDL in male and female patients were higher compared to controls, but this is not statistically significant. DISCUSSION AND CONCLUSION: In conclusion, lipid profile was altered in our patients, with high cholesterol level as the commonest derangement, particularly in men. Therefore, screening for lipid profile abnormalities could be considered in the treatment of acne patients. Dove 2020-01-21 /pmc/articles/PMC6982527/ /pubmed/32021370 http://dx.doi.org/10.2147/CCID.S230617 Text en © 2020 Sobhan et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Sobhan, Mohammadreza
Seif Rabiei, Mohammad Ali
Amerifar, Maryam
Correlation Between Lipid Profile and Acne Vulgaris
title Correlation Between Lipid Profile and Acne Vulgaris
title_full Correlation Between Lipid Profile and Acne Vulgaris
title_fullStr Correlation Between Lipid Profile and Acne Vulgaris
title_full_unstemmed Correlation Between Lipid Profile and Acne Vulgaris
title_short Correlation Between Lipid Profile and Acne Vulgaris
title_sort correlation between lipid profile and acne vulgaris
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982527/
https://www.ncbi.nlm.nih.gov/pubmed/32021370
http://dx.doi.org/10.2147/CCID.S230617
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