Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration

A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (...

Descripción completa

Detalles Bibliográficos
Autores principales: Soares, Liliana, Novais, Susana, Ferreira, António, Frazão, Orlando, Silva, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982736/
https://www.ncbi.nlm.nih.gov/pubmed/31877833
http://dx.doi.org/10.3390/s20010087
_version_ 1783491357275324416
author Soares, Liliana
Novais, Susana
Ferreira, António
Frazão, Orlando
Silva, Susana
author_facet Soares, Liliana
Novais, Susana
Ferreira, António
Frazão, Orlando
Silva, Susana
author_sort Soares, Liliana
collection PubMed
description A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% v/v of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time.
format Online
Article
Text
id pubmed-6982736
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-69827362020-02-28 Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration Soares, Liliana Novais, Susana Ferreira, António Frazão, Orlando Silva, Susana Sensors (Basel) Communication A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% v/v of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time. MDPI 2019-12-22 /pmc/articles/PMC6982736/ /pubmed/31877833 http://dx.doi.org/10.3390/s20010087 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Soares, Liliana
Novais, Susana
Ferreira, António
Frazão, Orlando
Silva, Susana
Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title_full Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title_fullStr Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title_full_unstemmed Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title_short Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title_sort detection of the crystallization process of paracetamol with a multi-mode optical fiber in a reflective configuration
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982736/
https://www.ncbi.nlm.nih.gov/pubmed/31877833
http://dx.doi.org/10.3390/s20010087
work_keys_str_mv AT soaresliliana detectionofthecrystallizationprocessofparacetamolwithamultimodeopticalfiberinareflectiveconfiguration
AT novaissusana detectionofthecrystallizationprocessofparacetamolwithamultimodeopticalfiberinareflectiveconfiguration
AT ferreiraantonio detectionofthecrystallizationprocessofparacetamolwithamultimodeopticalfiberinareflectiveconfiguration
AT frazaoorlando detectionofthecrystallizationprocessofparacetamolwithamultimodeopticalfiberinareflectiveconfiguration
AT silvasusana detectionofthecrystallizationprocessofparacetamolwithamultimodeopticalfiberinareflectiveconfiguration

Ejemplares similares