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Evaluation of Isoflavones as Bone Resorption Inhibitors upon Interactions with Receptor Activator of Nuclear Factor-κB Ligand (RANKL)

Receptor activator of nuclear factor-κB ligand (RANKL) is a cytokine responsible for bone resorption. It binds its receptor RANK, which activates osteoporosis. High levels of osteoprotegerin (OPG) competitively binding RANKL limit formation of ligand-receptor complexes and enable bone mass maintenan...

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Detalles Bibliográficos
Autores principales: Zakłos-Szyda, Małgorzata, Budryn, Grażyna, Grzelczyk, Joanna, Pérez-Sánchez, Horacio, Żyżelewicz, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982798/
https://www.ncbi.nlm.nih.gov/pubmed/31947859
http://dx.doi.org/10.3390/molecules25010206