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Evaluation of Isoflavones as Bone Resorption Inhibitors upon Interactions with Receptor Activator of Nuclear Factor-κB Ligand (RANKL)
Receptor activator of nuclear factor-κB ligand (RANKL) is a cytokine responsible for bone resorption. It binds its receptor RANK, which activates osteoporosis. High levels of osteoprotegerin (OPG) competitively binding RANKL limit formation of ligand-receptor complexes and enable bone mass maintenan...
Autores principales: | Zakłos-Szyda, Małgorzata, Budryn, Grażyna, Grzelczyk, Joanna, Pérez-Sánchez, Horacio, Żyżelewicz, Dorota |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982798/ https://www.ncbi.nlm.nih.gov/pubmed/31947859 http://dx.doi.org/10.3390/molecules25010206 |
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