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Design and Biological Evaluation of Colchicine-CD44-Targeted Peptide Conjugate in an In Vitro Model of Crystal Induced Inflammation

Gout is an inflammatory arthritis due to the joint deposition of monosodium urate (MSU) crystals. Phagocytosis of MSU crystals by tissue macrophages results in the generation of reactive oxygen species (ROS) and production of inflammatory cytokines and chemokines. Colchicine use in gout is limited b...

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Detalles Bibliográficos
Autores principales:	Zoghebi, Khalid A., Bousoik, Emira, Parang, Keykavous, Elsaid, Khaled A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982808/ https://www.ncbi.nlm.nih.gov/pubmed/31877739 http://dx.doi.org/10.3390/molecules25010046

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